Of the two well-known rodent models of human type 1 diabetes (the non-obese diabetic mouse and the BioBreeding rat) the mouse has become the model of choice ... MHC class II I-Aβ chain showed ...

Moreover, when GPR3 was genetically ablated in a mouse model of Alzheimer's disease, the levels of Aβ were dramatically reduced. Importantly, γ-secretase-mediated processing of Notch ...