Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.
More information: James R. O'Siorain et al, Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages, The FASEB Journal (2024). DOI: 10.1096/fj.202400508RR ...
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