Maintenance phase: use buprenorphine/naloxone sublingual films at the same buprenorphine dose as Day 2; if intolerant to naloxone, may adjust buprenorphine by 2mg or 4mg increments/decrements to ...

Taking buprenorphine while fentanyl is still active can push someone abruptly into withdrawal. So, they started giving patients small doses of the drug over a series of days to slowly build up ...