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Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.

Figure 1: Homologues of cellular cyclins encoded by the viruses KSHV (KS) and γMH68 (γ68) bind to one or more cellular cyclin-dependent kinases (CDKs) and phosphorylate an increased number of ...