Engineering the replication of target DNA through cloning, or changing its genetic code through mutations, are detail-oriented processes whose foibles can spell disaster. Caitlin Smith looks at ...

Still, the scientists say, this abundance of mutations could influence the function of a normal brain. “To what extent do these clonal mutations normally shape the development of the brain, in a ...

Clonal hematopoiesis develops when a single HSC acquires growth-promoting mutations and begins to churn out many, many clones of itself. Eventually, these mutated blood cells become over ...

However, in some cases, these stem cells undergo genetic mutations, a phenomenon known as clonal hematopoiesis. This mutation causes these altered cells to multiply rapidly, contributing to an ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution ... the researchers identified a new mutation mechanism, called ...

The study, published recently in the Proceedings of the National Academy of Sciences, reveals how a mutated gene called ASXL1 is involved in a disease called clonal hematopoiesis, a precursor to ...

rare examples of asexual species that reproduce by cloning. Each offspring is genetically identical to the parent, with little variation generation after generation. (Mutations do create a minor ...

In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell ...