The high accuracy or fidelity of semi-conservative DNA replication is the product of nucleotide template interaction, polymerase-enhanced base selectivity, exonuclease proofreading and the post ...

One is that the DNA template somehow becomes defective during replication, and causes the polymerase to pause (Figures 3 and 4a). For example, a DNA base can be chemically modified or ...

However, the behind-the-scenes process of analyzing forensic DNA is far more intricate, requiring careful interpretation of the data. Forensic DNA profiling uses polymerase chain reaction (PCR) to ...