In addition to demonstrating that folding drives disulfide bond formation, Anfinsen found that ... of scientists in both fields on solving the mechanism of protein folding. In 1961 the structure ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Disruptions in protein translocation to the ER or disulfide bond formation underlie several diseases, and understanding the mechanisms that govern these processes is essential in biology and ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo.

Many diseases are caused by disruptions in the formation of disulfide bonds or the translocation of proteins to the ER, and biology and medicine must comprehend the mechanisms underlying these ...