Artelo Biosciences Announces Successful Completion of First Cohort in a Phase 1 Study of ART26.12
The first selective Fatty Acid Binding Protein 5 inhibitor safely administered to human subjectsInitial safety and pharmacokinetic data expected ...
Nature1y
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
Adipocytes and macrophages jointly express two FABPs: A-FABP (also known as aP2/FABP4) and E-FABP (also known as mal1/FABP5), which are the best-studied FABPs. They play a central role in many ...
Benzinga.com27d
EXCLUSIVE: Artelo Biosciences Concludes First Cohort Of Healthy Volunteers Of FABP Inhibitor Program
ART26.12 is the lead compound in Artelo's proprietary Fatty Acid Binding Protein (FABP) platform and is believed to be the first-ever selective FABP5 inhibitor to enter clinical trials.
腾讯网15d
医脉通肝脏科
慢加急性肝衰竭（ACLF）是指在慢性肝病基础上出现的急性肝功能恶化，以肝内肝外器官衰竭和高病死率为主要特征的临床综合征。肝衰竭的发病机制复杂，相关生物标志物的探索有助于预测疾病的转归。免疫和炎症相关指标［可溶性CD163（sCD163）、可溶性甘露糖受体、尿中性粒细胞明胶酶相关脂蛋白］，氧化应激相关指标［晚期氧化 ...
电子工程专辑20d
基于钙钛矿纳米酶的光电化学/荧光双模式微流控传感平台
心型脂肪酸结合蛋白（H-FABP）是一种主要存在于心脏、骨骼肌和肾脏中的小分子蛋白，参与脂肪酸的转运和代谢，在心脏能量代谢中起关键作用。H-FABP可作为心脏损伤的早期生物标志物 ...