When there is enough product at the end of a reaction pathway (red macromolecule), it can inhibit its own synthesis by interacting with enzymes in the synthesis pathway (red arrow). Cells ...

Genes for some of the enzymes in a cell are expressed so that the enzymes are always present. Influencing their activity can control their rates of reaction. Different chemicals can influence ...

Antimicrobial design; targeted protein degradation; mTORC1 inhibition; enzyme structure-function studies. My laboratory uses approaches derived from both chemistry and biology. Projects include ...

Biosensors based on cholinesterase inhibition have been found to effectively detect biocides in milk, ensuring food safety ...