In this millenium, we will be required to answer such questions as: Will it be possible to treat ischemic heart disease by stimulating myocardial angiogenesis, and will it be feasible to cure ...

Hypoxia enhances proliferation, angiogenesis, metastasis, chemoresistance, and radioresistance of hepatocellular carcinoma (HCC); suppresses differentiation and apoptosis of HCC; and consequently ...

Central to this resistance is angiogenesis—the abnormal formation of blood vessels within tumors. These newly formed vessels exacerbate tumor hypoxia and obstruct the delivery of therapeutic ...

Central to this resistance is angiogenesis—the abnormal formation of blood vessels within tumors. These newly formed vessels exacerbate tumor hypoxia and obstruct the delivery of therapeutic ...

Yet, therapeutic resistance, hypoxia-induced angiogenesis, and immune evasion remain significant barriers. The advent of T-cell receptor (TCR) sequencing offers a transformative lens to unravel ...

Van Meir's research examines how genetic alterations and hypoxia induce changes in cell biology that promote tumor formation with particular emphasis on heterotypic cell-cell signaling, including ...