When the X-ray contrast medium was injected, the whole vasculature of the 9.5 day embryo was elucidated with LM, and the backscattered electron image and the secondary electron image of the identical ...
Finally, 10 years on, the trilogy is complete. Patrick Tam and Janet Rossant, two of the most respected mouse developmental biologists, have produced an exceptional book. Right from the outset, it ...
The Niswander lab investigates mouse models of embryonic development to provide insights into fundamental developmental processes, major human birth defects and potential clinical therapies. Her ...
Uniform Manifold Approximation and Projection (UMAP) plot integrating Velocity with Leiden analysis of mouse lung cells from late embryonic timepoints. Lineage tracing via green fluorescent protein ...
9 In addition, SOX-2 overexpression in mouse has been previously found ... This study shows that the embryonic airway epithelial cell markers SOX-2 and TTF-1 are retained in the cyst-lining epithelial ...
Unlike organoids, which model parts of single organs, the duo coaxed aggregates of mouse embryonic stem cells to carry out fundamental processes of development to become embryo-like entities, or ...
Clumps of embryonic stem cells given one brief molecular stimulation start arranging themselves in a way that resembles a mouse embryo, down to the timing of when the cells switch on particular ...
We found that at embryonic day 18.5, the alveolar airspaces were significantly wider in Daam2 homozygotes’ lungs compared to their wildtype counterparts (n=12, P<0.05). This indicates disruption to ...
Three-dimensional visualization of nerves (green) and blood vessels (magenta) in a mouse embryo. Developmental biologist Kat Hadjantonakis works to gain insights into the critical events that direct ...
Using patient tumors as well as a mouse model of lung cancer metastasis, our analyses identify regenerative cell types and lineage promiscuity in untreated primary tumors and reveal a range of ...