Objectives Intranasal nalbuphine could be a safe, efficacious and non-invasive alternative to parenteral pain medication in infants. We aimed to assess pharmacokinetics (PK) and tolerability of ...
We report the interim analysis of a phase 2 study of an extended-release (ER) oral formulation of the dual-acting κ-opioid receptor agonist/µ-opioid receptor antagonist nalbuphine (NAL) for ...
Trevi said the study’s primary endpoint was peak effect for “drug liking.”The study demonstrated statistically significant lower "drug liking" for the 81mg and 162mg doses of oral nalbuphine ...