The advantage of this approach is that, unlike in a structural equation model, these interactions do not need to be specified ahead of the test, making it a true discovery method. Although causal ...

Systematically integrate biological contextual information with causal estimates generated using Mendelian randomization Develop novel approaches to identifying, validating and prioritising potential ...

A genetic causal link between rheumatoid arthritis (RA) and an increased risk of traumatic and osteoporotic fractures ...