Only about 4% of candidate drugs reach the market. The main culprits of this failure are due to issues with dosing , exposure and toxicity. Join us as Dr. Paul Leeson shares how improving candidate ...
Each different substance has a different solubility. This table shows the solubility of substances in water at 20°C. Solubility is shown as the grams of a solute per 100 g of water.
With respect to the formulation of the drug, this comprises: release of the active ingredient, dissolution in the stomach and/or intestine, transport of the solid ... and its solubility in water ...
Cisplatin is one of the most widely used agents in the treatment of solid tumors ... the method may be generalized to other drugs showing low water solubility and lipophilicity.