A thrombopoietin agonist raises platelet counts in HCV-positive patients who are undergoing antiviral therapy. Cirrhotic patients who are infected with hepatitis C virus (HCV) often experience ...

leading to a low platelet count. Thrombopoietin Receptor Agonists (TPO-RAs): Medications that stimulate the production of platelets in the bone marrow. Bruton's Tyrosine Kinase (BTK): An enzyme ...

To further test their discovery, the team also vaccinated mice against bird flu, adding a drug called thrombopoietin that ups the production of platelets from megakaryocytes. The mice given this ...

that does not compete with thrombopoietin (TPO) for receptor binding. It functions by stimulating the growth of megakaryocytes, which are bone marrow cells responsible for platelet production.

Doptelet (avatrombopag) – an oral thrombopoietin receptor agonist – has been cleared to boost depleted levels of platelets in the blood of patients with ITP, an autoimmune clotting disorder ...

We study how various combinations of growth factors, including thrombopoietin produce mature megakaryocytes ... because the quality and quantity of platelets produced by these megakaryocytes are vital ...