The selective advantage for the establishment and, more interestingly, the maintenance of heterogeneity in tumors is unclear. Our results indicate that tumors benefit collectively from protecting ...

Gastrointestinal (GI) cancers account for 26% of the global cancer incidence and 35% of all cancer-related deaths. Although the top 5 cancers in this group ...

Squamous cancer is a heterogeneous disease with unique genomic and phenotypic features that differ markedly between individual patients and result in major differences in disease course and response ...

Our group utilises genome editing technologies, models, cultures and mass cytometry-based single cell approaches to experimentally model the cancer ecosystem. Dr Marco Bezzi leads the Tumour ...

The discovery that a subset of cells could affect a tumor’s overall aggressiveness got me interested in the study of heterogeneity in cancer. Heterogeneity is the focus of my lab today. Before the ...

A pioneering study has uncovered the complex and dual roles of neutrophils in cancer development, demonstrating their remarkable ability to both stimulate and suppress tumor growth.

Tumor heterogeneity remains a formidable obstacle in targeted cancer therapy, often leading to suboptimal treatment outcomes. This study presents an innovative approach that harnesses controlled ...