The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

How does the cell protect these strands from damage? How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is ...

Institute for Genomic Biology professor Sua Myong and physics professor Taekjip Ha led a team that discovered the mechanism by which the hepatitis C helicase unwinds DNA and RNA for replication.