The administration of chemotherapeutic drugs at maximum tolerated doses (MTDs) often induces dose-limiting toxicity in rapidly dividing tissues (intestines, bone marrow, and skin), and so patients ...

Chemotherapeutic agents are often used to treat cancer. They combat tumor growth, but also have a number of undesirable side effects. One of these is severe muscle wasting, known as ...

Home > Press release: How chemotherapy drug sorafenib causes ...

In addition to the many advances in targeted therapies and immunotherapies, new formulations and delivery mechanisms are emerging for existing agents, particularly for chemotherapeutic agents.

"Our findings will help us better understand the consequences of certain types of chemotherapeutic drugs that are used to treat patients and cause DNA damage. We've discovered that the IL-1α and ...

However, systemic chemotherapy can lead to significant adverse effects and limited tumour targeting. Bioactive glasses are clinically used for repairing small bone defects however these materials have ...