Namely, CRS induces hippocampal choline acetyltransferase protein expression and decreases nuclear STAT3 signaling. CRS also augments signaling activity, IL-1β and TNF-α expression and microglial ...

Western blot analysis was used to detect changes in col type I (138 kD), α-SMA, TGF-β1 (40−60 kD), p-ERK1/2 (42−44 kD), RhoA-GTP (22 kD), M1 (52 kD), M2 (70 kD), M3 (75 kD) and choline ...

Choline is a crucial nutrient that performs important roles in the human body. It is necessary for the functioning of cell membranes, neurotransmitters, and liver. While choline can be found in ...

Choline is an essential nutrient crucial for the development of the brain and nervous system, particularly during pregnancy. Although choline is found in numerous foods, it can be difficult to ...

Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of both upper and lower motor neurons. Despite decades of research, we still to date lack a cure or disease ...

Correspondence to Professor John T O'Brien, Department of Psychiatry, University of Cambridge, Cambridgeshire and Peterborough NHS Foundation Trust, Box 189, Level E4 Cambridge Biomedical Campus, ...

Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad 382355, Gujarat, India Department of Pharmacology and Toxicology, College of ...