Absence of Cap2 has an impact of neuronal development. In particular, dendritic complexity, the number and morphology of dendritic spines were dependent on CAP2. Furthermore, CAP2 is an important ...

Dynamic changes in the structural characteristics of the postsynaptic membrane and, in particular, of dendritic spines have been a topic of great interest over the last decade (reviewed in refs.

The study suggests that mutations in the Usp9X gene could be a potential cause of autism. These mutations disrupt the ...

In this manuscript, Griesius et al analyze the dendritic integration properties of NDNF and OLM interneurons, and suggest that the supralinear NMDA receptor-dependent synaptic integration may be ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Plasmacytoid dendritic cells (pDCs) are a special subtype of dendritic cells with the morphology of plasma cells. pDCs produce massive amounts of type I interferon (IFN-I), which was originally found ...

Researchers have identified a unique mitochondrial process in CA2 neurons that supports learning, memory, and social ...

We found that Chrdl1 KO mice displayed enhanced synaptic plasticity, and in response to stroke, deficits such as dendritic spine degeneration, impaired GluA2-AMPAR distribution, and motor dysfunction ...

Estuardo Robles is a neuroscientist with broad interests in how nervous systems use sensory information extracted from their surroundings to direct behavioral programs. Previous research focused on ...

Feb. 3, 2025 — Researchers have uncovered how perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep. The study could help scientists understand ...

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances.