2018a). Following this logic, the laboratory of Oxburgh has recently shown that the asynchronous mixing of hPSCs-derived NPCs with epithelializing nephrons over time results in the generation of ...

Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number, is a common cause of pediatric renal failure and adult-onset disease. Genetic studies ...

Ready to start planning your care? Call us at 800-525-2225 to make an appointment.

Cardiovascular diseases are the number one cause of death worldwide and greatly impact quality of life and medical costs. Enormous effort has been made in research to obtain new tools for efficient ...

From 2010 to 2022, 12% of patients in a U.S. database underwent delayed surgery for distal radius fractures. Smoking status, comorbidities, insurance type and geographic region were associated ...

Nedd4 is a ubiquitin protein ligase composed of a C2 domain, three (or four) WW domains and a ubiquitin ligase Hect domain. Nedd4 was demonstrated to bind the epithelial sodium channel (αβγENaC ...

Finally, proteases active along the nephron and distal urinary tract might affect the urinary peptide fragments detected by UPP analysis. However, in a placebo-controlled study of a dipeptidyl ...

An Asian woman in her 70s was started on trimethoprim-sulfamethoxazole (TMP-SMX) for treatment of her left fourth toe osteomyelitis. During the course of her therapy, she developed renal tubular ...

Phosphorus is one of the most abundant minerals in the human body and is required, in association with calcium, to maintain bone integrity and mineralization. The maintenance of intracellular and ...

aCenter for Renal Translational Medicine/Institute for Metabolomic Medicine, University of California San Diego, San Diego, CA, United States bDepartment of Clinical and Molecular Medicine, Faculty of ...

Clinical Physiology provides diagnostic methods to detect and evaluate dysfunction of various organs and systems in the body such as the heart, peripheral vessels, lungs, kidneys, gastrointestinal ...