with a focus on the impact of chemical and physical properties on drug solubility and permeability. The likelihood of drug interactions increases for highly soluble drugs, manifesting through ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The simulation of antral conditions for estimating drug apparent equilibrium ...

Zerion Pharma & Aché collaborate to exploit the Dispersome technology for improvement of two marketed drug products: Copenhagen, Denmark Saturday, January 25, 2025, 16:00 Hrs [IS ...

Ligand Pharmaceuticals Incorporated (Nasdaq: LGND) today announced that Chief Executive Officer Todd Davis and Chief ...

Two separate research teams have found ways to create short chains of amino acids, termed peptides, for the purpose of ...

"We found that using leukemic cell lines can lead to misleading results in drug discovery," said Wilhelm. "These cell lines do not grow in the same way as cells taken from patients." The efficacy ...

We created a computational and experimental large-scale metabolic profiling framework that enabled us to map metabolic effects for 1,520 diverse drugs. This platform revealed new modes of action ...

Drug repurposing, or identifying new uses for existing drugs, has emerged as an alternative to traditional drug discovery processes involving de novo synthesis. Drugs that are currently approved or ...