Negative-pressure pulmonary edema (NPPE) occurs when a large, negative intrathoracic pressure is generated against an obstructed upper airway, causing fluid to shift into the lung interstitium.

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Correspondence to British Thoracic Society, 17, Doughty Street, London WC1N 2PL, UK; bts{at}brit-thoracic.org.uk and Dr Charlotte E Bolton, Nottingham Respiratory Research Unit, University of ...

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