This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

S16a, see Methods for more details). Each local patch carried 10 competing species that ... These interactions can further change the distribution of plasmids among different species, alter the ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

Pre-clinical studies indicate that efficient retrovirus-mediated gene transfer into hematopoietic stem cells and progenitor cells can be achieved by co-localizing retroviral particles and target ...

Gene expression is the ... including ribosomal RNA (rRNA), transfer RNA (tRNA) or small nuclear RNA (snRNA). A study describes the development of PERFF-seq, a method to ‘FISH’ out rare cells ...

Organoids were cultured from healthy donor iPSC sources and differentiated using the human iPSC-derived Cerebral Organoid ...

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Furthermore, this nanomachine exhibited gene transfer efficiency to the central ... Gene therapy is a treatment method that involves the administration of genes or gene-modified cells into the ...

Messenger RNA can travel between different types of stem cells through tunnel-like structures, as revealed by a new study. By ...

Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics. Generation of a stable, high-performance, monoclonal cell line producing a ...