Germline development is the development of the ... and divide and differentiate to produce sperm and egg, the male and female gametes. A conserved feature of metazoan meiosis is that it occurs ...

At the cellular level, pieces of important genetic information, called small RNA, have the ability to introduce important ...

Background: Medulloblastoma is the most common malignant brain tumor in children. Most cases are sporadic, but well characterized germline alterations in APC, ELP1, GPR161, PTCH1, SUFU, and TP53 ...

Risk of proteinuria with atezolizumab plus bevacizumab versus lenvatinib in first-line systemic treatment for hepatocellular carcinoma. End-of-life (EOL) outcomes and healthcare utilization for ...

Figure 1. The frequency and distribution of cancer susceptibility genes (CSGs) with more than one pathogenic/likely pathogenic germline mutation detected in patients with esophageal squamous cell ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

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Accurate specification of female and male germ cells during embryonic development is critical for sexual reproduction. Primordial germ cells (PGCs) are the bipotential precursors of mature gametes ...