Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

We used sections stained with hematoxylin and eosin to compare histological morphology and to quantify anaphase bridges and pyknotic nuclei. Unstained sections were stained for apoptotic cells ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

As the sister chromatids separate from each other and are pulled toward opposite ends of the cell during anaphase, mitochondria are still fully fragmented. During telophase/cytokinesis, chromosomes ...

In mitosis, tension by microtubules is generated between sister kinetochores (left, Figure 1B), whereas it is generated between homologous kinetochores (right). The bend spindle in anaphase I is due ...