The proteasome is a large protein complex in the cytoplasm of eukaryotic and archaeal cells responsible for proteolysis of proteins that have one or more poly-ubiquitin post-translational ...

Mitochondria are cytoplasmic organelles found in most eukaryotic cells. They are formed from an outer membrane, a highly invaginated inner membrane containing cristae, and a matrix. Mitochondria ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...