Half of renally-cleared rivaroxaban is cleared as unchanged drug and half as inactive metabolites. ‡Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole ...

In patients undergoing upper gastrointestinal endoscopic submucosal dissection, risk for ischemic stroke was lower with rivaroxaban than with dabigatran. Rivaroxaban was associated with a lower risk ...

The disciplines of pharmacology and physiology touch on virtually every field of the biomedical sciences, presenting endless opportunities to discover disease mechanisms and develop new treatments.

These substances, which include pharmaceutical products and biomarkers, have a broad range of applications. Biotechnology's intersection with pharmacology holds promise for developing innovative ...

Pharmacology is a branch of biomedical science, encompassing clinical pharmacology, that is concerned with the effects of drugs/pharmaceuticals and other xenobiotics on living systems, as well as ...

Purpose The pharmacology, pharmacokinetics, efficacy, and safety of apixaban are reviewed. Summary Apixaban is an oral, direct, selective factor Xa inhibitor with a rapid onset of action.

Introduction: There is continued unmet medical need for new medicines across countries especially for cancer, immunological diseases, and orphan diseases. However, there are growing challenges with ...

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.

1.4 Associated with connective tissue disease, HIV infection, portal hypertension, congenital heart disease, schistosomiasis ALK-1 indicates activin receptor-like kinase 1; BMPR2, bone morphogenetic ...