Methods: AS percent-splice-in (PSI) data of 430 patients with PTC were downloaded from the TCGA SpliceSeq database. We successfully identified recurrence-free survival (RFS)-associated AS events ...

In the present study, we establish the concept of immediate early splicing (IES). We show that a group of splicing events, mostly retention of introns, shows a fast and transient splicing switch upon ...

To argue that AS accounts for differences among cells or tissues, it must be shown that the expression of the splice variants is differentially regulated in those environments. With this in mind, we ...

Alternative splicing is where exon or intron skipping can occur. For HPVs, several main splice events can occur (Figures 2 & 3). The first is generated by splicing from a splice donor site in the ...

Envisagenics, an AI-driven biotechnology company revolutionizing RNA splicing research and therapeutics, has appointed Sudhir Rao, M.S., MBA as Chief Business Officer (CBO) to expand and strengthen ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

We defined SERBP1’s interactome, uncovered novel roles in splicing, cell division and ribosomal biogenesis, and showed its participation in pathological stress granules and Tau aggregates in Alzheimer ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...