Cover picture: Inspired by the Review by Jung-Soon Mo, Hyun Woo Park and Kun-Liang Guan. Illustrated by Sandra Krahl.

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...

Miraculous, divine intervention because of obedience to God. Abraham does not hesitate to sacrifice Isaac. But thou shalt go unto my country, and to my kindred, and take a wife unto my son Isaac. And ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

T-1101 is under development for the treatment of advanced malignancies, refractory solid tumors. The drug candidate is a new chemical entity (NCE) administered through oral route. It acts by targeting ...

T-1101 is under clinical development by Taivex Therapeutics and currently in Phase I for Advanced Malignancy. According to GlobalData, Phase I drugs for Advanced Malignancy does not have sufficient ...

Bacterial and viral virulence mechanisms have long been used as a tool to provide insight into intracellular signaling pathways ... exclusively on serine and threonine residues, was aided in ...

Implication of protein kinase CK2 in ER stress signalling pathways. (uXBP1: unspliced XBP1; sXBP1: spliced XBP1). cing by miRNA technology causes an increased dephosphorylation and activation of PERK ...

Transcripts carrying premature stop codon are usually degraded by nonsense-mediated mRNA decay (NMD) pathway (Lykke-Andersen and Jensen ... In our design, the deletion between two gRNAs target sites ...

In 2024, Canada launched several new pathways to permanent residence and has made major changes to existing pathways. The below table showcases these updates for a clearer overview. Francophone ...