Urate reabsorption by urate transporter-1 is partly suppressed at the proximal tubule lumen membrane by the uricosurics benzbromarone, probenicid and losartan. Fenofibrate could also inhibit urate ...

Concerning drugs, 57.0% of the patients had received a ULT at any one time, most frequently allopurinol, and 48.3% received colchicine. Uricosurics (probenecid and lesinurad) were almost never ...

With a CAGR of 4.3% from 2025 to 2034, the global refractory gout market is expected to increase from USD 1,050.21 million in 2024 to USD 1,599.24 million in 2034. A type of arthritis called gout ...

With a CAGR of 4.3% from 2025 to 2034, the global refractory gout market is expected to increase from USD 1,050.21 million in 2024 to USD 1,599.24 million in 2034. A type of arthritis called gout ...

Objective Verinurad (RDEA3170) is a high-affinity, selective URAT1 inhibitor in development for treating gout and asymptomatic hyperuricaemia. This study evaluated the pharmacodynamics, ...