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126 Azurophilic granules (primary) are the first to form and contain myeloperoxidase, cathepsin G, and defensin to destroy microorganisms. These are followed by the formation of specific granules ...

The drug candidate is a HER2 specific IgG-based antibody drug conjugate carrying DAR8 of the Ed-04 payload technology, composed of a potent topoisomerase 1 inhibitor and a serum-stable linker that is ...

Hepatitis B (sometimes referred to as hep B) is a liver infection caused by the hepatitis B virus (HBV). It typically causes symptoms like stomach pain, dark urine, fatigue, fever, jaundice (yellowing ...

Cell Lysate Cathepsin B (CTSB) Activity Assay Cell lysates were produced as described above. 2 μl of the cell lysates were incubated with 20 μM fluorogenic CTSB substrate (Z-RR-AMC; Enzo; ...

Here we proposed to evaluate the importance of Cathepsin B on NLRP3 inflammasome assembly and activation. Using Cathepsin B –/– BMDMs (Bone Marrow-Derived Macrophages), we first show that Cathepsin B ...