A recent study by a team from Chiba University has demonstrated a promising approach for fighting antibiotic resistance by identifying a compound, V-161, that inhibits a sodium-pumping enzyme critical ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been ...

A new study has uncovered a critical role for the enzyme Glucose-6-phosphatase 2 (G6PC2) in regulating blood sugar levels.

Biosensors based on cholinesterase inhibition have been found to effectively detect biocides in milk, ensuring food safety ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. A multiplex drug screening platform ... can be ...

Nonribosomal peptide synthetase (NRPS) enzymes are essential in creating important medications, such as penicillin and cyclosporine. This is done through a multi-step process where the enzymes ...

1Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts. 2Department of Biological Engineering, Massachusetts Institute of Technology, ...

This constitutes the first indication of the apparent induction of a glucuronide-conjugating enzyme system by phenobarbital in man and therefore may also represent the first therapeutic ...

Testing ALDH was the next step. We set up an inhibition assay in test tubes. In the assay, we measured how fast the enzyme ALDH breaks down acetaldehyde. Then, we added the suspected inhibitors ...

University of Missouri, Department of Chemistry, 125 Chemistry Building, Columbia, Missouri 65211, United States University of Missouri, Department of Biochemistry, 125 Chemistry Building, Columbia, ...