引言空间转录组学技术能够在生物组织原位绘制复杂的基因表达图谱，正在革新我们对发育生物学、免疫学、肿瘤学以及疾病病理学的理解【1】。然而，迄今为止，该领域的研究范围主要集中在信使RNA（mRNA）表达的分析上。真核细胞的转录组由动态多样的RNA分子组成 ...

She also notes that paraffin embedding can weaken the signal in an IHC assay, such that detection of lesser-expressed proteins can become difficult. On the plus side, the antibodies that perform ...

Formalin-fixed paraffin-embedded (FFPE) samples are a valuable oncology resource, providing a wealth of data on cancer ...

We use state of the art Sakura Tissue-Tek VIP Processor, and the Sakura Tissue-Tek paraffin embedding center. A variety of advanced programs and protocols for different types of tissue are available ...

The first was a set of 96 paraffin-embedded cancer samples. For these samples, 74 mutations had been previously identified using conventional dideoxy sequencing. The OncoCarta Panel identified 70 ...

1. Nature｜樊荣/唐力团队同期二连发，癌症免疫治疗再创突破！Type-1 免疫被视为抗肿瘤的主要免疫应答类型，而 Type-2 免疫在肿瘤发生、发展与治疗中的作用更为复杂，常与免疫抑制微环境相关并促进肿瘤生长。尽管如此，越来越多的研究显示 ...

Fixation in cold ethanol and hand processing for IHC (Sainte-Marie G. A paraffin embedding technique for studies employing immunofluorescence. J Histochem Cytochem 10:250-256, 1962) Colitis models for ...

In this important study, the authors used a zebrafish model and scRNAseq analysis to show that a subset of keratinocytes within melanoma microenvironment highly up-regulate Twist and undergo ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...

To support these efforts, Precision for Medicine has an inventory of 3.5 million formalin-fixed paraffin-embedded tissues together with a network of over 100 hospitals for prospective tissue ...

The following is a summary of “Single-nucleus RNA-sequencing Reveals a MET+ Oligodendrocyte Subpopulation that Promotes ...

(4) Denervated bands of Schwann cells. Multifocal diabetic neuropathy. Cross section of a paraffin-embedded superficial peroneal nerve specimen from a patient with a subacute progressive ...