Retrospective study of fluoropyrimidine chemotherapy dosing and toxicity in patients with screen-detected deleterious DPYD gene variants. Real-world treatment patterns, healthcare resource utilization ...

Research Institute for Light-induced Acceleration System (RILACS), Osaka Metropolitan University, 1-2 Gakuencho, Nakaku, Sakai, Osaka 599-8570, Japan Department of Physics, Graduate School of Science, ...

[45] These mutations constitute signature spectrums of different cancer subtypes, suggesting a new way to classify cancers based on genomic mutation instead of originating organs. Similar ...

Personalizing anticancer therapy therefore relies upon identifying each patient's cancer-specific driver mutations. Although routine analysis of cancer genomes using NGS is an aim for the short to ...