Scientists have uncovered a blood-based molecular signature that can predict vaccine durability. Could this change ...

A thrombopoietin agonist raises platelet counts in HCV-positive patients who are undergoing antiviral therapy. Cirrhotic patients who are infected with hepatitis C virus (HCV) often experience ...

To further test their discovery, the team also vaccinated mice against bird flu, adding a drug called thrombopoietin that ups the production of platelets from megakaryocytes. The mice given this ...

For instance, a longitudinal study of two patients with CTP revealed that fluctuations in platelet counts were linked to cycling levels of thrombopoietin (TPO), a hormone that regulates platelet ...

that does not compete with thrombopoietin (TPO) for receptor binding. It functions by stimulating the growth of megakaryocytes, which are bone marrow cells responsible for platelet production.

We study how various combinations of growth factors, including thrombopoietin produce mature megakaryocytes ... because the quality and quantity of platelets produced by these megakaryocytes are vital ...

Doptelet (avatrombopag) – an oral thrombopoietin receptor agonist – has been cleared to boost depleted levels of platelets in the blood of patients with ITP, an autoimmune clotting disorder ...