The Ins and Outs of Cathepsins - PubMed Central (PMC)
Cathepsins are the most abundant lysosomal proteases that are mainly found in acidic endo/lysosomal compartments where they play a vital role in intracellular protein degradation, …
Cysteine cathepsins: From structure, function and regulation …
2012年1月1日 · In addition to the aspartic cathepsin D, cysteine cathepsins have a key role among the lysosomal proteases. They belong to the clan CA of cysteine peptidases, which are …
What are Cathepsins (CTS)? - News-Medical.net
2021年3月15日 · What are Cathepsins (CTS)? Cathepsins are proteases, which are enzymes that are responsible for degrading proteins. There are around 12 different types of cathepsins. …
The Ins and Outs of Cathepsins - MDPI
2020年7月13日 · Cathepsins are the most abundant lysosomal proteases that are mainly found in acidic endo/lysosomal compartments where they play a vital role in intracellular protein …
Cathepsin - an overview | ScienceDirect Topics
Cathepsins are proteases with serine, cysteine, or aspartic acid residues as the nucleophiles, which are vital for digestion, coagulation, immune response, adipogenesis, hormone liberation, …
The Ins and Outs of Cathepsins: Physiological Function and Role in ...
2020年7月13日 · Cathepsins are the most abundant lysosomal proteases that are mainly found in acidic endo/lysosomal compartments where they play a vital role in intracellular protein …
Cathepsins: Key modulators of cell death and ... - ScienceDirect
2008年12月1日 · In this review, we will discuss the role of cathepsins in caspase-dependent and -independent apoptotic pathways and hypothesize that lysosomes, in which cathepsins are …
Cysteine Cathepsins and Their Extracellular Roles: Shaping the ...
In this review, we highlight the most important findings that establish cysteine cathepsins as important players in the extracellular space and discuss their roles that reach beyond …
Cathepsins: Proteases that are vital for survival but can also ... - PubMed
Cathepsins are proteases with serine, cysteine, or aspartic acid residues as the nucleophiles, which are vital for digestion, coagulation, immune response, adipogenesis, hormone liberation, …
A Review of Small Molecule Inhibitors and Functional Probes of …
Human cathepsin L belongs to the cathepsin family of proteolytic enzymes with primarily an endopeptidase activity. Although its primary functions were originally thought to be only of a …
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