The Molecular and Functional Characteristics of HLA-G and the ...
Human leukocyte antigen G (HLA-G) mediates maternal-fetal immune tolerance. It is also considered an immune checkpoint in cancer since it may mediate immune evasion and thus …
Recent Advances in Our Understanding of HLA-G Biology: Lessons …
HLA-G is a HLA-class Ib molecule with potent immunomodulatory activities, which is expressed in physiological conditions, where modulation of the immune response is required to avoid …
HLA-G Gene - GeneCards | HLAG Protein | HLAG Antibody
Dec 25, 2024 · HLA-G (Major Histocompatibility Complex, Class I, G) is a Protein Coding gene. Diseases associated with HLA-G include Asthma and Severe Pre-Eclampsia . Among its …
The role of HLA-G in immunity and hematopoiesis - PMC
In this review, we report the latest advances of HLA-G-mediated tolerance at both molecular and cellular levels, and the functions of HLA-G unrelated to the immune response.
HLA-G major histocompatibility complex, class I, G [ (human)]
HLA-G expression correlates with prognostic markers of a poor B-CLL outcome, mainly Binet clinical staging and CD38 expression by B-CLL cells, which indicates that this parameter may …
Some Basic Aspects of HLA-G Biology - PMC - PubMed Central …
Human leukocyte antigen-G (HLA-G) is a major histocompatibility complex class I antigen encoded by a gene on chromosome 6p21. It differs from classical HLA class I molecules by its …
HLA-G major histocompatibility complex, class I, G [Homo …
Jan 4, 2025 · HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy …
Editorial: The Biological and Clinical Aspects of HLA-G
Feb 18, 2021 · HLA-G features limited genetic variation, very restricted tissue expression, and immune tolerogenic functions, being a ligand of immune inhibitory receptors. HLA-G is now …
Biological Characteristics of HLA-G and Its Role in Solid Organ ...
Jun 13, 2022 · HLA-G is a regulatory molecule, first described in fetal cytotrophoblasts during pregnancy, and is thought to play a role in protecting the fetus from destruction by the …
HLA-G: from biology to clinical benefits - ScienceDirect
Mar 1, 2008 · HLA-G is a nonclassical HLA class I molecule initially described as being selectively expressed at the maternal-fetal interface on cytotrophoblast cells. HLA-G was first depicted as …
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