Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction with the dopaminergic system.

Neurotensin (NT) is a 13-amino-acid peptide originally isolated in 1973 from bovine hypothalami. 1 This neuropeptide is found in the central nervous system (CNS), as well as in the gastrointestinal tract. However, this review will focus on the CNS effects of NT.

Neurotensin (NT) is a neuropeptide that is closely associated with, and is thought to modulate, dopaminergic and other neurotransmitter systems involved in the pathophysiology of various mental disorders. This review outlines data implicating NT in ...

In this review, we describe briefly the basic biology of this neuropeptide, and then we consider the strengths and the weaknesses of the data that suggest a role for neurotensin in schizophrenia, drug abuse, Parkinson's disease, pain, central control of blood pressure, eating disorders, cancer, neurodegenerative disorders and inflammation.

Neurotensin is a 13 amino acids containing neuropeptide that is released during a meal. It is produced in neurons of the ARC, PVN, and DMH as well as in the periphery, where it acts on the digestive and cardiovascular system.

Neurotensin is a regulator of insulin secretion in pancreatic beta-cells. Int. J. Biochem. Cell Biol. 42 1681–1688 [Google Scholar] Beraud-Dufour S., Coppola T., Massa F., Mazella J. (2009). Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells. Int. J. Biochem.

Neurotensin (NT), an endogenous brain-gut peptide, has a close anatomical and functional relationship with the mesocorticolimbic and neostriatal dopamine system. Dysregulation of NT neurotransmission in this system has been hypothesized to …

The peptide neurotensin has been studied for more than 30 years. Although it is widely distributed in the central and peripheral nervous systems, neurotensin has been more intensely studied with regard to its interactions with the central dopamine system.

2013年9月15日 · Neurotensin (NT) is a tridecapeptide, which – since its discovery in 1973 – has been demonstrated to be involved in the control of various physiological activities in both the central nervous system and in the periphery. Its biological …

Neurotensin (NT) is a 13-amino acid neuropeptide widely distributed in the CNS that has been involved in the pathophysiology of many neural and psychiatric disorders. There are three known neurotensin receptors (NTSRs), which mediate multiple actions, and form the neurotensinergic system in conjunct …