Pyrrolidine - Wikipedia
Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH 2) 4 NH. It is a cyclic secondary amine, also classified as a saturated heterocycle. It is a colourless liquid that is miscible with water and most organic solvents.
Pyrrolidine | C4H9N | CID 31268 - PubChem
Pyrrolidine is a cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family. It is a saturated organic heteromonocyclic parent, a member of pyrrolidines and an azacycloalkane.
Pyrrolidine 99 123-75-1 - MilliporeSigma
Pyrrolidine is a heterocyclic building block used in organic synthesis and a scaffold for biologically active compounds.
Therapeutic potential of pyrrole and pyrrolidine analogs: an update
Pyrrolidine (saturated pyrrole) analog; telaprevir is an antiviral drug, peptidomimetic used in combination therapy to treat chronic Hepatitis C Virus (HCV) infection. This drug inhibits NS3/4A, a serine protease encoded by HCV genotype 1 and SARS-CoV-2 3CL proteases.
Recent insights about pyrrolidine core skeletons in pharmacology
Pyrrolidines, pyrrolidine-alkaloids, and pyrrolidine-based hybrid molecules are present in many natural products and pharmacologically important agents. Their key roles in pharmacotherapy make them a versatile scaffold for designing and developing novel biologically active compounds and drug candidates.
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel ...
2021年8月10日 · In this review, we report bioactive molecules with target selectivity characterized by the pyrrolidine ring and its derivatives, including pyrrolizines, pyrrolidine-2-one, pyrrolidine-2,5-diones and prolinol described in the literature from 2015 to date.
Pyrrolidine alkaloids and their promises in pharmacotherapy
2020年1月9日 · Pyrrolidine alkaloids possess a five-membered nitrogen-containing ring. This group of compounds has not been fully investigated, although numerous important alkaloids of this class have been recognized for their promising biological effects.
Pyrrolidine: Properties, Structure, Preparation And Uses
2024年2月21日 · Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH 2) 4 NH. It is a cyclic secondary amine, also classified as a saturated heterocycle. It is a colourless liquid that is miscible with water and most organic solvents.
Therapeutic potential of pyrrole and pyrrolidine analogs: an …
2022年1月25日 · This review mainly focuses on the therapeutic potential of pyrrole, pyrrolidine, and its fused analogs, more specifically anticancer, anti-inflammatory, antiviral, and antituberculosis. Further, this review summarizes more recent reports on the pyrrole, pyrrolidine analogs, and their biological potential.
Pyrrolidine - an overview | ScienceDirect Topics
Pyrrolidine is a saturated five-membered cyclic compound containing nitrogen in the ring, known as tetrahydropyrrole or azacyclopentane. It is structurally flexible, basic in nature, and found in various natural alkaloids and synthetic chemistry applications.