Regulatory authorities may enforce the standards presented in the USP and NF, but because recognition of the USP and NF may vary by country, users should understand applicable laws and regulations.

Only where a special, quantitative solubility test is given in the individual monograph, and is designated by a test heading, is it a test for purity. The approximate solubilities of Pharmacopeial and National Formulary substances are indicated by …

Only where a special, quantitative solubility test is given in the individual monograph, and is designated by a test heading, is it a test for purity. The approximate solubilities of Pharmacopeial and Na- tional Formulary substances are indicated by the descriptive terms in …

Only where a special, quantitative solubility test is given in the individual monograph, and is designated by a test heading, is it a test for purity. The approximate solubilities of Pharmacopeial and Na- tional Formulary substances are indicated by the descriptive terms in …

1 Reference Tables DESCRIPTION AND SOLUBILITY Description and Relative Solubility of USP and NF Articles Add the following: Add the following: • Cetirizine Hydrochloride: White to almost white powder. Irinotecan Hydrochloride: Pale yellow to yellow crystal- Freely soluble in water; practically insoluble in acetone and inline powder.

The solubility of one substance in another is a measure of the degree of molecular mixing between the two pure substances at thermodynamic equilibrium. The composition of a saturated solution, expressed as a proportion of a designated solute in a designated solvent, represents this

1 Solubility data for compounds that ordinarily are liquids at 25 are expressed in terms of the ratio of the volume of solute to the volume of solvent; i.e., 1 mL dissolved in mL of solvent. 2 Liquid phase only; silicon dioxide remains as a residue in these solvents.

The information is provided for those who use, prepare, and dispense drugs, solely to indicate descriptive and solubility properties of an article complying with monograph standards.

An amount equivalent to 100,000 USP Units is soluble in 10 mL of water and in 10 mL of saline TS.

The solubility of the main component is obtained by extending the solubility line (BC) through the y-axis. The point of interception on the y -axis is the extrapolated solubility, in mg per g, and is a constant for a given compound.