Tumor antigen - Wikipedia
Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with …
Tumor Antigens - Hematology and Oncology - Merck Manual …
Tumor-specific antigens (TSAs) are unique to tumor cells. TSAs and TAAs typically are portions of intracellular molecules expressed on the cell surface often associated with molecules encoded …
Uncovering the Tumor Antigen Landscape: What to Know about …
Naturally presented antigens in the human leucocyte antigen-1 (HLA-I) complex on the tumor surface are the main protagonists in evocating a specific anti-tumor CD8+ T cell response. …
Cancer Antigen 19-9 (CA 19-9): Tumor Marker Blood Test
2023年6月7日 · The CA 19-9 test is a tumor marker blood evaluation to measure the body’s response to cancer treatment. Learn the normal ranges and how to evaluate results.
Tumor Antigens - Holland-Frei Cancer Medicine - NCBI Bookshelf
For something to be a tumor antigen, it must be recognized by specific immune effector cells and/or antibodies and be produced by tumor cells. Among the tumor antigens, some may be …
Tumor Antigen - an overview | ScienceDirect Topics
Tumor antigens are the most important markers for the recognition and elimination of tumor cells by CTLs. Tumor antigens mainly are peptides or glycoproteins.
Antigen presentation in cancer: insights into tumour ... - Nature
2021年3月9日 · To date, clinically effective CD8 + T cell responses appear to target predominantly antigens derived from tumour-specific mutations that accumulate in cancer, …
Categories of Tumor Antigens - Holland-Frei Cancer Medicine
Tumor-associated antigens (TAA) can derive from any protein or glycoprotein synthesized by the tumor cell. TAA proteins can reside in any subcellular compartment of the tumor cell; ie, they …
Update on Tumor Neoantigens and Their Utility: Why It’s Good To …
Neoantigens, which are peptide antigens derived from mutated genes and presented on major histocompatibility complexes (MHC), are perhaps the most widely recognized of these foreign …
Uncovering the Tumor Antigen Landscape: What to Know about the ... - PubMed
2020年6月23日 · The current review is intended to define what are today known as tumor antigens, with a main focus on CTL antigenic peptides. We also review the techniques …