Gastrinoma - Wikipedia
Gastrinomas are neuroendocrine tumors (NETs), usually located in the duodenum or pancreas, that secrete gastrin and cause a clinical syndrome known as Zollinger–Ellison syndrome (ZES). [1][2][3] A large number of gastrinomas develop in the pancreas or duodenum, with near-equal frequency, and approximately 10% arise as primary neoplasms in lymph ...
Gastrinoma - StatPearls - NCBI Bookshelf
2023年7月28日 · Gastrinomas are neuroendocrine tumors characterized by the secretion of gastrin with resultant excessive gastric acid production, causing severe peptic ulcer disease and diarrhea, a combination referred to as the Zollinger-Ellison syndrome (ZES). Gastrinomas are the most common functional and malignant pancreatic endocrine tumors.
Gastrinoma: Symptoms, Treatment, and Diagnosis - Healthline
2018年9月18日 · If you have a gastrinoma, your body secretes large amounts of gastrin, resulting in a higher level of stomach acid. This higher level can cause the formation of ulcers in your stomach and small...
Gastrinoma: What Is It, Symptoms, Diagnosis | Osmosis
2025年1月6日 · Gastrinomas are rare, usually small tumors that can originate from G cells in the pancreas, stomach or small intestine. Most gastrinomas are malignant. Gastrinomas can be solitary or develop in clusters, and can occur sporadically or be associated with multiple endocrine neoplasia type 1 (MEN-1).
Zollinger-Ellison syndrome (gastrinoma): Clinical ... - UpToDate
Zollinger-Ellison syndrome (ZES) is caused by secretion of gastrin by duodenal or pancreatic neuroendocrine tumors (gastrinomas). The annual incidence of gastrinomas is 0.5 to 2 per million population [3-5]. Most patients are diagnosed between the ages of 20 and 50, with a higher incidence in males as compared with females [6].
Gastrinoma - Gastrointestinal Disorders - MSD Manual …
A gastrinoma is a gastrin-producing tumor usually located in the pancreas or the duodenal wall. Gastric acid hypersecretion and aggressive, refractory peptic ulceration result (Zollinger-Ellison syndrome). Diagnosis is by measuring serum gastrin levels. Treatment is proton pump inhibitors and surgical removal.
Gastrinoma - Hormonal and Metabolic Disorders - Merck Manual …
A gastrinoma is a neuroendocrine tumor that produces excessive levels of the hormone gastrin, which stimulates the stomach to secrete acid and enzymes, causing peptic ulcers. Gastrinomas are usually located in the pancreas or duodenum (the first segment of the small intestine).
Gastrinoma - Endocrine and Metabolic Disorders - MSD Manual ...
A gastrinoma is a gastrin-producing tumor usually located in the pancreas or the duodenal wall. Gastric acid hypersecretion and aggressive, refractory peptic ulceration result (Zollinger-Ellison syndrome). Diagnosis is by measuring serum gastrin levels. Treatment is proton pump inhibitors and surgical removal.
Gastrinoma: Background, Pathophysiology, Epidemiology - Medscape
2021年12月3日 · A gastrinoma is a gastrin-secreting tumor that can occur in the pancreas, although it is most commonly found in the duodenum. Duodenal wall gastrinomas have been identified in 40-50% of patients.
Gastrinoma | Radiology Reference Article | Radiopaedia.org
2024年10月9日 · Gastrinomas are usually malignant and they are frequently multiple and often extrapancreatic (90% located in the gastrinoma triangle). They are more commonly located in the duodenum than in the pancreas.
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