Cathepsin B in programmed cell death machinery: mechanisms of …
2023年4月8日 · Cathepsin B (CatB), a cysteine protease, is primarily localized within subcellular endosomal and lysosomal compartments. It is involved in the turnover of intracellular and …
Cathepsin B: Multiple roles in cancer - PMC - PubMed Central (PMC)
Proteases, including intracellular proteases, play roles at many different stages of malignant progression. Our focus here is cathepsin B, a lysosomal cysteine cathepsin. High levels of …
The Ins and Outs of Cathepsins - PubMed Central (PMC)
Cathepsins on the cell surface are known to be involved in plasma membrane repair. Cathepsin B released from keratinocytes attaches to cells surface where it is known to be involved in …
Cathepsin B: Basis Sequence: Mouse - PMC - PubMed Central (PMC)
Cathepsin B is a member of the papain-like family of cysteine proteases and is synthesized as a preproenzyme of 339 amino acids with a calculated molecular weight of approximately 38 kDa …
Cathepsin B - an overview | ScienceDirect Topics
Cathepsin-B is a lysosomal cysteine protease. During physical exercise, it is released from skeletal muscle cells. Cathepsin-B was found to pass through the blood–brain barrier and …
Behind every smile there's teeth: Cathepsin B's function in …
2022年4月1日 · Cathepsin B (CatB) is a very abundant lysosomal protease with endo- and carboxydipeptidase activities and even ligase features. In this review, we will provide a general …
Cathepsin B - SpringerLink
2018年1月1日 · Cathepsin B, originally named cathepsin B1, was the first and remains the best-characterized member of the C1 family of papain-like, lysosomal cysteine peptidases. First …
Distinct Cleavage Properties of Cathepsin B Compared to Cysteine ...
2023年7月17日 · Activated microglia are the main cellular source of interleukin-1β in the brain. Cathepsin B is associated with the production and secretion of interleukin-1β through pyrin …
Cathepsin B launches an apoptotic exit effort upon cell death ...
2016年2月29日 · In this apoptotic exit strategy, cathepsin B’s proteolytic activity results in apoptosis-inducing Bid and removes apoptosis-preventing Bcl-xl.
CTSB Gene - Cathepsin B
2024年12月24日 · CTSB (Cathepsin B) is a Protein Coding gene. Diseases associated with CTSB include Keratolytic Winter Erythema and Hyperparathyroidism, Neonatal Severe . Among its …
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